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1

The transcriptional regulator Rel is essential for antigen receptor-mediated stimulation of mature T cells but dispensable for positive and negative selection of thymocytes and T cell apoptosis

Andreas Strasser, Raelene J. Grumont, Maureen L. Stanley, Steve Gerondakis

Journal:

European Journal of Immunology

Year:

1999

Language:

english

File:

PDF, 176 KB

english, 1999

2

c-Rel phenocopies PKCθ but not Bcl-10 in regulating CD8+ T-cell activation versus tolerance

Elissa K. Deenick, Leslie Po, Laurence Chapatte, Kiichi Murakami, Yong-Chen Lu, Alisha R. Elford, Samuel D. Saibil, Jürgen Ruland, Steve Gerondakis, Tak W. Mak, Pamela S. Ohashi

Journal:

European Journal of Immunology

Year:

2010

Language:

english

File:

PDF, 378 KB

english, 2010

3

Mice lacking the p50/NF-κB gene exhibit defects in T cell proliferation in response to various activation stimuli

T. Pohl, S. Gerondakis

Journal:

Immunology Letters

Year:

1997

Language:

english

File:

PDF, 363 KB

english, 1997

4

The regulation and roles of Rel/NF-κB transcription factors during lymphocyte activation

Steve Gerondakis, Raelene Grumont, Ian Rourke, Mathis Grossmann

Journal:

Current Opinion in Immunology

Year:

1998

Language:

english

File:

PDF, 636 KB

english, 1998

5

Immunoglobulin JHrearrangement in a T-cell line reflects fusion to theDHlocus at a sequence lacking the nonamer recognition signal

Steve Gerondakis, Ora Bernard, Suzanne Cory, Jerry M. Adams

Journal:

Year:

1988

Language:

english

File:

PDF, 461 KB

english, 1988

6

Structure and expression of mouse germline immunoglobulin γ3 heavy chain transcripts induced by the mitogen lipopolysaccharide

Steve Gerondakis, Clara Gaff, David J. Goodman, Raelene J. Grumont

Journal:

Year:

1991

Language:

english

File:

PDF, 991 KB

english, 1991

7

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNFα Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

Thomas Kaufmann, Philipp J. Jost, Marc Pellegrini, Hamsa Puthalakath, Raffi Gugasyan, Steve Gerondakis, Erika Cretney, Mark J. Smyth, John Silke, Razq Hakem, Philippe Bouillet, Tak W. Mak, Vishva M. D

Journal:

Year:

2009

Language:

english

File:

PDF, 1.41 MB

english, 2009

8

Distinct roles in NKT cell maturation and function for the different transcription factors in the classical NF-κB pathway

Stankovic, Sanda, Gugasyan, Raffi, Kyparissoudis, Konstantinos, Grumont, Raelene, Banerjee, Ashish, Tsichlis, Philip, Gerondakis, Steve, Godfrey, Dale I

Journal:

Immunology & Cell Biology

Year:

2010

Language:

english

File:

PDF, 844 KB

english, 2010

9

Bcl-2 transgene expression fails to prevent fatal hepatocyte apoptosis induced by endogenous TNFα in mice lacking RelA

Gugasyan, R, Christou, A, O'Reilly, L A, Strasser, A, Gerondakis, S

Journal:

Cell Death & Differentiation

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

10

Loss of the BH3-only protein Bid does not rescue RelA-deficient embryos from TNF-R1-mediated fatal hepatocyte destruction

Kaufmann, T, Gugasyan, R, Gerondakis, S, Dixit, V M, Strasser, A

Journal:

Cell Death & Differentiation

Year:

2006

Language:

english

File:

PDF, 112 KB

english, 2006

11

Regulating B-cell activation and survival in response to TLR signals

Gerondakis, Steve, Grumont, Raelene J, Banerjee, Ashish

Journal:

Immunology & Cell Biology

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

12

Coordinating TLR-activated signaling pathways in cells of the immune system

Banerjee, Ashish, Gerondakis, Steve

Journal:

Immunology & Cell Biology

Year:

2007

Language:

english

File:

PDF, 151 KB

english, 2007

13

Genetic approaches in mice to understand Rel/NF-κB and IκB function: transgenics and knockouts

Gerondakis, Steve, Grossmann, Mathis, Nakamura, Yukio, Pohl, Thomas, Grumont, Raelene

Journal:

Year:

1999

Language:

english

File:

PDF, 155 KB

english, 1999

14

Unravelling the complexities of the NF-κB signalling pathway using mouse knockout and transgenic models

Gerondakis, S, Grumont, R, Gugasyan, R, Wong, L, Isomura, I, Ho, W, Banerjee, A

Journal:

Year:

2006

Language:

english

File:

PDF, 257 KB

english, 2006

15

Organization and Expression of Murine Immunoglobulin Genes

Jerry M. Adams, David J. Kemp, Ora Bernard, Nicholas Gough, Elizabeth Webb, Brett Tyler, Steven Gerondakis, Suzanne Cory

Journal:

Immunological Reviews

Year:

1981

Language:

english

File:

PDF, 6.45 MB

english, 1981

16

Dangerous liaisons

Steve Gerondakis

Journal:

Current Biology

Year:

1991

Language:

english

File:

PDF, 703 KB

english, 1991

17

Autoreactive T Cells Escaping Thymic Deletion in REL-B Deficient Mice Depend on Dendritic Cell-encoded REL-B for Control of Autoimmunity

Brendan O' Sullivan, Saparna Pai, Shayna Street, Kelli MacDonald, Steve Gerondakis, Geoffrey Hill, Ranjeny Thomas

Journal:

Clinical Immunology

Year:

2010

Language:

english

File:

PDF, 58 KB

english, 2010

18

Get Away Special (GAS) educational applications of space flight

Gerondakis, G.G.

Journal:

IEEE Transactions on Education

Year:

1991

Language:

english

File:

PDF, 971 KB

english, 1991

19

NF-κB subunit specificity in hemopoiesis

Steve Gerondakis, Ashish Banerjee, George Grigoriadis, Ajithkumar Vasanthakumar, Raffi Gugasyan, Tom Sidwell, Raelene J Grumont

Journal:

Immunological Reviews

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

20

Illumina WG-6 BeadChip strips should be normalized separately

Wei Shi, Ashish Banerjee, Matthew E Ritchie, Steve Gerondakis, Gordon K Smyth

Journal:

BMC Bioinformatics

Year:

2009

Language:

english

File:

PDF, 665 KB

english, 2009

21

Structure of the Gene Encoding the Murine Dual Specificity Tyrosine-Threonine Phosphatase PAC1

Steve Gerondakis, Cathy Economou, Raelene J. Grumont

Journal:

Year:

1994

File:

PDF, 200 KB

1994

22

The Mitogen-Induced Increase in T Cell Size Involves PKC and NFAT Activation of Rel/NF-κB-Dependent c-myc Expression

Raelene Grumont, Peter Lock, Michael Mollinari, Frances M Shannon, Anna Moore, Steve Gerondakis

Journal:

Year:

2004

Language:

english

File:

PDF, 585 KB

english, 2004

23

Simultaneous expression of germline γ1 and ε immunoglobulin heavy chain transcripts in single murine splenic B-cells

David J. Goodman, Steve Gerondakis

Journal:

Molecular Immunology

Year:

1997

Language:

english

File:

PDF, 1.12 MB

english, 1997

24

The role of Rel/NF-κB transcription factors in B lymphocyte survival

Steve Gerondakis, Andreas Strasser

Journal:

Seminars in Immunology

Year:

2003

Language:

english

File:

PDF, 129 KB

english, 2003

25

PU.1/Spi-B Regulation of c-rel Is Essential for Mature B Cell Survival

Cheng-Jun Hu, Sridhar Rao, Diana L. Ramirez-Bergeron, Lee Ann Garrett-Sinha, Steve Gerondakis, Marcus R. Clark, M.Celeste Simon

Journal:

Year:

2001

Language:

english

File:

PDF, 441 KB

english, 2001

26

B Cell Growth Is Controlled by Phosphatidylinosotol 3-Kinase-Dependent Induction of Rel/NF-κB Regulated c-myc Transcription

Raelene J Grumont, Andreas Strasser, Steve Gerondakis

Journal:

Year:

2002

Language:

english

File:

PDF, 647 KB

english, 2002

27

New insights into the roles of ReL/NF-κB transcription factors in immune function, hemopoiesis and human disease

Mathis Grossmann, Yukio Nakamura, Raelene Grumont, Steve Gerondakis

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

1999

Language:

english

File:

PDF, 191 KB

english, 1999

28

Tissue-Specific Effects of the Nuclear Factor κB Subunit p50 on Myocardial Ischemia-Reperfusion Injury

Stefan Frantz, Jochen Tillmanns, Peter J. Kuhlencordt, Isabel Schmidt, Anna Adamek, Charlotte Dienesch, Thomas Thum, Steve Gerondakis, Georg Ertl, Johann Bauersachs

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 385 KB

english, 2007

29

The TACI Receptor Regulates T-Cell-Independent Marginal Zone B Cell Responses through Innate Activation-Induced Cell Death

Figgett, William A., Fairfax, Kirsten, Vincent, Fabien B., Le Page, Mélanie A., Katik, Indzi, Deliyanti, Devy, Quah, Pin Shie, Verma, Pali, Grumont, Raelene, Gerondakis, Steve, Hertzog, Paul, O’Reilly

Journal:

Year:

2013

Language:

english

File:

PDF, 2.32 MB

english, 2013

30

NF-κB control of T cell development

Gerondakis, Steve, Fulford, Thomas S, Messina, Nicole L, Grumont, Raelene J

Journal:

Nature Immunology

Year:

2013

Language:

english

File:

PDF, 1.00 MB

english, 2013

31

Translocation of the myc cellular oncogene to the immunoglobulin heavy chain locus in murine plasmacytomas is an imprecise reciprocal exchange

Gerondakis, Steven, Cory, Suzanne, Adams, Jerry M.

Journal:

Year:

1984

Language:

english

File:

PDF, 1.04 MB

english, 1984

32

[Part 1: Biological Sciences] || mRNA for Surface Immunoglobulin γ Chains Encodes a Highly Conserved Transmembrane Sequence and a 28-Residue Intracellular Domain

Brett M. Tyler, Alan F. Cowman, Steven D. Gerondakis, Jerry M. Adams and Ora Bernard

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.25 MB

english, 1982

33

[Part 1: Biological Sciences] || Transcriptionally Active DNA Region That Rearranges Frequently in Murine Lymphoid Tumors

Jerry M. Adams, Steven Gerondakis, Elizabeth Webb, Jan Mitchell, Ora Bernard and Suzanne Cory

Journal:

Proceedings of the National Academy of Sciences

Year:

1982

Language:

english

File:

PDF, 1.32 MB

english, 1982

34

[Part 1: Biological Sciences] || Cellular myc Oncogene is Altered by Chromosome Translocation to an Immunoglobulin Locus in Murine Plasmacytomas and is Rearranged Similarly in Human Burkitt Lymphomas

Jerry M. Adams, Steven Gerondakis, Elizabeth Webb, Lynn M. Corcoran and Suzanne Cory

Journal:

Proceedings of the National Academy of Sciences

Year:

1983

Language:

english

File:

PDF, 1.64 MB

english, 1983

35

Rel-Deficient T Cells Exhibit Defects in Production of Interleukin 3 and Granulocyte--Macrophage Colony-Stimulating Factor

Steve Gerondakis, Andreas Strasser, Donald Metcalf, George Grigoriadis, Jean-Pierre Y. Scheerlinck and Raelene J. Grumont

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 968 KB

english, 1996

36

The Combined Absence of the Transcription Factors Rel and RelA Leads to Multiple Hemopoietic Cell Defects

Mathis Grossmann, Donald Metcalf, Julie Merryfull, Amer Beg, David Baltimore and Steve Gerondakis

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.69 MB

english, 1999

37

Apaf-1 and Caspase-9 Do Not Act as Tumor Suppressors in myc-Induced Lymphomagenesis or Mouse Embryo Fibroblast Transformation

Clare L. Scott, Martin Schuler, Vanessa S. Marsden, Alex Egle, Marc Pellegrini, Dobrila Nesic, Steve Gerondakis, Stephen L. Nutt, Douglas R. Green and Andreas Strasser

Journal:

The Journal of Cell Biology

Year:

2004

Language:

english

File:

PDF, 1.91 MB

english, 2004

38

NFAT but not NF- B is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells

Ulleras, E., Karlberg, M., Moller Westerberg, C., Alfredsson, J., Gerondakis, S., Strasser, A., Nilsson, G.

Journal:

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

39

MEK inhibitors as a chemotherapeutic intervention in multiple myeloma

Chang-Yew Leow, C, Gerondakis, S, Spencer, A

Journal:

Blood Cancer Journal

Year:

2013

Language:

english

File:

PDF, 340 KB

english, 2013

40

Loss of c-REL but not NF-κB2 prevents autoimmune disease driven by FasL mutation

O'Reilly, L A, Hughes, P, Lin, A, Waring, P, Siebenlist, U, Jain, R, Gray, D H D, Gerondakis, S, Strasser, A

Journal:

Cell Death & Differentiation

Year:

2015

Language:

english

File:

PDF, 4.45 MB

english, 2015

41

The NF- B Transcription Factor c-Rel Is Required for Th17 Effector Cell Development in Experimental Autoimmune Encephalomyelitis

Chen, G., Hardy, K., Pagler, E., Ma, L., Lee, S., Gerondakis, S., Daley, S., Shannon, M. F.

Journal:

The Journal of Immunology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

42

Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells

Banerjee, A., Gugasyan, R., McMahon, M., Gerondakis, S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2006

Language:

english

File:

PDF, 1.07 MB

english, 2006

43

Differential Role for c-Rel and C/EBP / in TLR-Mediated Induction of Proinflammatory Cytokines

Lu, Y.-C., Kim, I., Lye, E., Shen, F., Suzuki, N., Suzuki, S., Gerondakis, S., Akira, S., Gaffen, S. L., Yeh, W.-C., Ohashi, P. S.

Journal:

The Journal of Immunology

Year:

2009

Language:

english

File:

PDF, 563 KB

english, 2009

44

NF- B Couples Protein Kinase B/Akt Signaling to Distinct Survival Pathways and the Regulation of Lymphocyte Homeostasis In Vivo

Jones, R. G., Saibil, S. D., Pun, J. M., Elford, A. R., Bonnard, M., Pellegrini, M., Arya, S., Parsons, M. E., Krawczyk, C. M., Gerondakis, S., Yeh, W.-C., Woodgett, J. R., Boothby, M. R., Ohashi, P.

Journal:

The Journal of Immunology

Year:

2005

Language:

english

File:

PDF, 770 KB

english, 2005

45

NF- B RelA (p65) Is Essential for TNF- -Induced Fas Expression but Dispensable for Both TCR-Induced Expression and Activation-Induced Cell Death

Zheng, Y., Ouaaz, F., Bruzzo, P., Singh, V., Gerondakis, S., Beg, A. A.

Journal:

The Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 695 KB

english, 2001

46

c-Rel Regulates Ezh2 Expression in Activated Lymphocytes and Malignant Lymphoid Cells

Neo, W. H., Lim, J. F., Grumont, R., Gerondakis, S., Su, I.-h.

Journal:

Journal of Biological Chemistry

Year:

2014

Language:

english

File:

PDF, 3.72 MB

english, 2014

47

Glucocorticoid-Induced TNF Receptor Expression by T Cells Is Reciprocally Regulated by NF- B and NFAT

Zhan, Y., Gerondakis, S., Coghill, E., Bourges, D., Xu, Y., Brady, J. L., Lew, A. M.

Journal:

The Journal of Immunology

Year:

2008

Language:

english

File:

PDF, 716 KB

english, 2008

48

c-Rel Is Required for Chromatin Remodeling Across the IL-2 Gene Promoter

Rao, S., Gerondakis, S., Woltring, D., Shannon, M. F.

Journal:

The Journal of Immunology

Year:

2003

Language:

english

File:

PDF, 397 KB

english, 2003

49

Mice lacking the c-rel proto-oncogene exhibit defects in lymphocyte proliferation, humoral immunity, and interleukin-2 expression.

Kontgen, F, Grumont, R J, Strasser, A, Metcalf, D, Li, R, Tarlinton, D, Gerondakis, S

Journal:

Genes & Development

Year:

1995

Language:

english

File:

PDF, 4.48 MB

english, 1995

50

Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4.

Journal:

Proceedings of the National Academy of Sciences

Year:

1990

Language:

english

File:

PDF, 1.16 MB

english, 1990